Our laboratory is part of the Microbial Sciences Institute and the Department of Ecology and Evolutionary Biology at Yale University. Our work lies at the interface between microbial ecology and the evolution of microbial behavior, with a focus on the molecules that microbes secrete to their environment and the interactions these molecules mediate. 



10/19/2017: Our laboratory's first preprint is out! A wonderful piece of work by visiting student Joshua Goldford, in collaboration with the entire postdoc cohort that started the lab together: Nanxi, Djordje, Sylvie and Alicia. Congratulations to all of them!

12/30/2016: We close the year with two new publications by former group members: Joe's paper was accepted at J. Roy. Soc: Interface, and Clarissa's paper just came out in Cell Systems. Congrats to Joe and Clarissa! It was also great fun to collaborate with our friends Angela DePace and Jane Kondev on these projects!

10/01/2016: Our lab welcomes two new postdoctoral scientists: Dr. Nanxi Lu, who is joining us in the fall, and Dr. Sylvie Estrela who will join us in February. We also welcome graduate student Jean Vila, who is rotating with us.

07/01/2016: Our lab has relocated to Yale University’s West Campus, where Alvaro has accepted a position as Assistant Professor in the Department of Ecology & Evolutionary Biology.

07/01/2016: Alvaro was awarded a Young Investigator Grant from the Human Frontier Science Program. We will collaborate with two other groups developing models of host-associated microbial population dynamics.

07/01/2016: Our lab got a Scialog seed grant from the Simons Foundation to understand microbial diversity in complex laboratory ecosystems. We will be working in collaboration with Pankaj Mehta (BU) in this exciting project.



Emergent simplicity in microbial community assembly. 
Joshua Goldford*, Nanxi Lu*, Djordje Bajic, Sylvie Estrela, Mikhail Tikhonov, Alicia Sanchez-Gorostiaga, Daniel Segre, Pankaj Mehta, and Alvaro Sanchez
BioRxiv (2017) 

Cooperators trade off ecological resilience and evolutionary stability in public goods games
Joseph Rauch, Jane Kondev and Alvaro Sanchez
Journal of the Royal Society Interface (2017) 

Combinatorial gene regulation through kinetic control of the transcription cycle
Clarissa Scholes, Angela H DePace* and Alvaro Sanchez* 
Cell Systems (2017)

Dynamics of a producer-freeloader ecosystem on the brink of collapse
Andrew Chen*, Alvaro Sanchez*, Lei Dai and Jeff Gore
Nature Communications (2014) 

Eco-evolutionary dynamics of complex social strategies in microbial communities
Kyle Harrington and Alvaro Sanchez
Communicative and Integrative Biology (2014) 

Genetic determinants and cellular constraints in noisy gene expression
Alvaro Sanchez and Ido Golding
Science (2013) 

Feedback between population and evolutionary dynamics determines the fate of social microbial populations
Alvaro Sanchez and Jeff Gore
PLOS Biology (2013) 



Alvaro will give a seminar at the Widely Applied Mathematics Seminar Series at Harvard School of Engineering and Applied Sciences on November 30, 2017

Alvaro will give a seminar at the University of Cologne Evolution Colloquium on March 7 2018

Alvaro will speak at the Stochastic Models in Ecology & Evolutionary Biology Workshop in Venice, Italy in April 5-7 2018

Alvaro will give a seminar at the University of Minnesota BioTechnology Institute on May 5 2018

Alvaro is Co-organizing an ASPEN Summer Conference on the Physical Principles Governing the Organization of Microbial Communities at the ASPEN Center for Physics, June 3-24 2018