Our laboratory is part of the Microbial Sciences Institute and the Department of Ecology and Evolutionary Biology at Yale University. Our work lies at the interface between systems biology and microbial community ecology and evolution. Our lab is largely interested in predicting (1) How microbes will evolve in a given, known environment, (2) What microbial communities will assemble in a given, known environment and (3) How microbes will behave in a given, known environment. To that end, we are particularly interested in understanding how the molecules microbes secrete to the environment, such as nutrients, toxins, etc., mediate community assembly and evolution. 



Our lab members will be giving seminars and presentations at the following venues:

  • Alvaro will give the Integrative Biology Department Seminar at UC Berkeley on Sept 19 2019

  • Alvaro will give a talk at the Jackson Laboratories on November 1 2019

  • Alvaro will give a department seminar at Georgia Tech in February 20 2020



On the deformability of an empirical fitness landscape by microbial evolution.  Djordje Bajic*, Jean C.C. Vila*, Zachary D. Blount and Alvaro Sanchez (2018) PNAS 

Emergent simplicity in microbial community assembly. Joshua Goldford*, Nanxi Lu*, Djordje Bajic, Sylvie Estrela, Mikhail Tikhonov, Alicia Sanchez-Gorostiaga, Daniel Segre, Pankaj Mehta, and Alvaro Sanchez (2018) Science 

High-order interactions dominate the functional landscape of microbial consortia
Alicia Sanchez-Gorostiaga*, Djordje Bajic*, Melisa Osborne, Juan F. Poyatos and Alvaro Sanchez (2018)  BioRxiv

Cooperators trade off ecological resilience and evolutionary stability in public goods games
Joseph Rauch, Jane Kondev and Alvaro Sanchez (2017)  Journal of the Royal Society Interface