Our laboratory is part of the Microbial Sciences Institute and the Department of Ecology and Evolutionary Biology at Yale University. Our work lies at the interface between systems biology and microbial community ecology and evolution. An important focus of the lab is understanding how the molecules microbes secrete to the environment, such as nutrients, toxins, etc., mediate the assembly and the evolution of microbial communities. 



08.03.2018: Congrats to Josh, Nanxi, Djordje, Sylvie and Alicia! Our paper Emergent Simplicity in Microbial Community Assembly is out today in Science.

05.20.2018: Nanxi and Sylvie will be giving talks at the 2018 ISME meeting in Leipzig, Germany, on August 12-17

04.02.2018: Djordje and Jean's new preprint is in bioRxiv. In collaboration with Zack Blount (Michigan State), we have investigated the deformability of an empirical fitness landscape. 

03.15.2018: Nanxi and Alicia's new preprint is out! A fun collaboration with Mikhail Tikhonov at Stanford to investigate collective effects in microbial invasions and community coalescence. Congrats to all!

03.12.2018: Sylvie and Djordje have been selected to give talks at the 2018 ESEB-SSB-SSE-ASN Joint Evolution Meeting in Montpellier. Congratulations to both of them!



On the deformability of an empirical fitness landscape by microbial evolution.  Djordje Bajic*, Jean C.C. Vila*, Zachary D. Blount and Alvaro Sanchez BioRxiv (2018) 

Cohesiveness in microbial community coalescence.  Nanxi Lu, Alicia Sanchez-Gorostiaga, Mikhail Tikhonov and Alvaro Sanchez BioRxiv (2018) 

Emergent simplicity in microbial community assembly. Joshua Goldford*, Nanxi Lu*, Djordje Bajic, Sylvie Estrela, Mikhail Tikhonov, Alicia Sanchez-Gorostiaga, Daniel Segre, Pankaj Mehta, and Alvaro Sanchez
Science (2018) 

Cooperators trade off ecological resilience and evolutionary stability in public goods games
Joseph Rauch, Jane Kondev and Alvaro Sanchez Journal of the Royal Society Interface (2017) 

Dynamics of a producer-freeloader ecosystem on the brink of collapse. Andrew Chen*, Alvaro Sanchez*, Lei Dai and Jeff Gore Nature Communications (2014) 

Eco-evolutionary dynamics of complex social strategies in microbial communities Kyle Harrington and Alvaro Sanchez Communicative and Integrative Biology (2014) 

Genetic determinants and cellular constraints in noisy gene expression Alvaro Sanchez and Ido Golding Science (2013) 

Feedback between population and evolutionary dynamics determines the fate of social microbial populations Alvaro Sanchez and Jeff Gore PLOS Biology (2013) 



Alvaro is Co-organizing an ASPEN Summer Conference on the Physical Principles Governing the Organization of Microbial Communities at the ASPEN Center for Physics, June 3-24 2018

Sylvie and Djordje have been both selected to give talks at the 2018 ESEB-SSB-SSE-ASN joint evolution meeting in Montpellier. Jean will be presenting a poster at the meeting too.

Sylvie and Nanxi will give talks, and Chang-Yu will present a poster at ISME meeting in Leipzing, August 12-17 2018

Alvaro will give the Yale School of Public Health Department of Epidemiology and Microbial Diseases Seminar on October 11 2018

Alvaro will give the Biophysics Seminar at Princeton on October 22 2018