Our laboratory is part of the Microbial Sciences Institute and the Department of Ecology and Evolutionary Biology at Yale University. Our work lies at the interface between microbial ecology and the evolution of microbial behavior, with a focus on the molecules that microbes secrete to their environment and the interactions these molecules mediate. 



12/30/2016: We close the year with two new publications by former group members: Joe's paper was accepted at J. Roy. Soc: Interface, and Clarissa's paper just came out in Cell Systems. Congrats to Joe and Clarissa! It was also wonderful to collaborate with our friends Angela DePace and Jane Kondev on these projects!

10/01/2016: Our lab welcomes two new postdoctoral scientists: Dr. Nanxi Lu, who is joining us in the fall, and Dr. Sylvie Estrela who will join us in February. We also welcome graduate student Jean Vila, who is rotating with us.

07/01/2016: Our lab has relocated to Yale University’s West Campus, where Alvaro has accepted a position as Assistant Professor in the Department of Ecology & Evolutionary Biology.

07/01/2016: Alvaro was awarded a Young Investigator Grant from the Human Frontier Science Program. We will collaborate with two other groups developing models of host-associated microbial population dynamics.

07/01/2016: Our lab got a Scialog seed grant from the Simons Foundation to understand microbial diversity in complex laboratory ecosystems. We will be working in collaboration with Pankaj Mehta (BU) in this exciting project.



Cooperators trade off ecological resilience and evolutionary stability in public goods games
Joseph Rauch, Jane Kondev and Alvaro Sanchez
Journal of the Royal Society Interface (2017) 

Combinatorial gene regulation through kinetic control of the transcription cycle
Clarissa Scholes, Angela H DePace* and Alvaro Sanchez* 
Cell Systems (2017)

Phenotypic states become increasingly sensitive to perturbations near a bifurcation in a synthetic gene network
Kevin Axelrod, Alvaro Sanchez and Jeff Gore
eLife (2015) 

Dynamics of a producer-freeloader ecosystem on the brink of collapse
Andrew Chen*, Alvaro Sanchez*, Lei Dai and Jeff Gore
Nature Communications (2014) 

Eco-evolutionary dynamics of complex social strategies in microbial communities
Kyle Harrington and Alvaro Sanchez
Communicative and Integrative Biology (2014) 

Genetic determinants and cellular constraints in noisy gene expression
Alvaro Sanchez and Ido Golding
Science (2013) 

Feedback between population and evolutionary dynamics determines the fate of social microbial populations
Alvaro Sanchez and Jeff Gore
PLOS Biology (2013) 



Alvaro will attend the 2017 HFSP awardee meeting in Lisbon, on July 9-12 2017

Alvaro will speak at the International Workshop on Systems Biology and the Molecular Economy of Microbial Communities in Trieste, Italy on July 3-7 2017.

Alvaro and Djordje will participate in the NIMBios Investigative workshop in pan-microbial trait ecology on June 14-16 

Alvaro will speak at the 2017 UCNC meeting that will take place at the University of Arkansas on June 5-9 2017

Alvaro will attend the Scialog Meeting: Molecules Come To Life on April 27-29 2017

Alvaro is giving a Yale Institute of Biospheric Sciences Seminar on April 21 2017

Alvaro will speak at the Center for Infectious Disease Dynamics at Penn State on September 15 2016